Is Glucose Toxic to Cells? Answers from the LIRKO Mouse and More ...
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I briefly interrupt Thermodenialgate reports to revisit the LIRKO mouse. But first, a little fun blast from the past. A few years ago now I did a series on fat tissue regulation that involved various receptor and gene knockout mice. I had a little fun making (low graphics tech) characters out of Star Wars Lego figures. First came C3KO , a mouse deficient in acylation stimulating protein, ASP, production. Shortly thereafter came Obi No Leptinobi .