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Low Carbohydrate, High Fat Diet Increases C-Reactive Protein during Weight Loss

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Low Carbohydrate, High Fat Diet Increases C-Reactive Protein during Weight Loss Janet W. Rankin, PhD and Abigail D. Turpyn  Journal of the American College of Nutrition, Vol. 26, No. 2, 163-169 (2007) Studied Variable: Dietary Carbohydrate Variables Measured: Body weight, IL-6, CRP, urinary 8-epi-prostaglandin, FBG, FFA (fasting) Variables controlled for: Caloric intake Protocol Summary: Subjects were ed into two groups followed calorie restricted (~1360 kcal/d) diets varied in composition: LC = 58F/12C/30P ; HC = 24F/59C/18P. Weight, inflammatory markers (IL-6 and CRP) and oxidative stress (8-epi) were measured weekly. Human Study Gender:  Women Age:  adult, premenopausal Number of Participants: 29 Weight Status: Overweight BMI 32.1 ± 5.4 kg/m2 Health Status: weight stable for at least 6 months, nonsmokers, sedentary, otherwise healthy and unmedicated Study Duration: 4 weeks Summary of results: * LC lost a bit more weight (3.8 ± 1.2 kg LC vs. 2.6 ± 1.7 HC, p=0.04)