I finally found the paper I've been alluding to here for a while, but have some other things in the works both for this blog and in my "real life" so that I'll just do a bookmark for now. Keith Frayn's Metabolic Regulation is just a gift that keeps on giving as in re-reading some parts that led to a blurb on FFA's citing one author of this review.
Sudden cardiac death: the lost fatty acid hypothesis
8 comments:
Nice find. I'll add that to the list of things that can be caused by Insulin Resistance.
You were right, I am enjoying Frayn's Metabolic Regulation (I got the 2010 edition - $44 for a "used" one that's actually brand new on Amzon). It's well written and covers pretty much everything at some level, and all hangs together. A great way to brush up my biochemistry and get the big picture, which is often missing in discussions of individual nutrients or processes.
I can see some of the new addition in Google books and he doesn't include ASP in the fat description which is disappointing. Because he DOES mention it as a "potent stimulator of fatty acid esterification in adipocytes" on p.136. and include the relationship between ASP and inflammatory pathways too. The technicality is that ASP isn't a "hormone". *sigh*
Perhaps ASP is a bigger actor in the cycle in and out of the adipocyte and insulin for the cycle within. The FA/trig cycle definitely includes release into the whole body, of which some portion is taken back up into the adipocytes, although more is cleared in the systemic tissues.
Man would I love to be a fly on the wall on a Taubes/Frayn conversation >8)
Sheesh ... my typos are bad today. That's new EDition!
I was chuffed to see Jack Salway's name mentioned in Frayn's book. I have two of Salway's books. I recommend both of them although there is some overlap. Links to Amazon in How stuff works.
Chuffed? I suppose I could look that up in some "urban dictionary", but I'd rather make more work for you ;-)
Oops! Chuffed (to bits) :-)
Thanks! Sounds like it would mean the opposite, kinda like miffed but that didn't make sense. :)
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