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“To kill an error is as good a service as, and sometimes even better than, the establishing of a new truth or fact”
~ Charles Darwin (it's evolutionary baybeee!)

Saturday, February 5, 2011

Free Fatty Acids & Sudden Cardiac Death

I finally found the paper I've been alluding to here for a while, but have some other things in the works both for this blog and in my "real life" so that I'll just do a bookmark for now.  Keith Frayn's Metabolic Regulation is just a gift that keeps on giving as in re-reading some parts that led to a blurb on FFA's citing one author of this review.

Sudden cardiac death: the lost fatty acid hypothesis

8 comments:

Nigel Kinbrum said...

Nice find. I'll add that to the list of things that can be caused by Insulin Resistance.

Margaret said...

You were right, I am enjoying Frayn's Metabolic Regulation (I got the 2010 edition - $44 for a "used" one that's actually brand new on Amzon). It's well written and covers pretty much everything at some level, and all hangs together. A great way to brush up my biochemistry and get the big picture, which is often missing in discussions of individual nutrients or processes.

CarbSane said...

I can see some of the new addition in Google books and he doesn't include ASP in the fat description which is disappointing. Because he DOES mention it as a "potent stimulator of fatty acid esterification in adipocytes" on p.136. and include the relationship between ASP and inflammatory pathways too. The technicality is that ASP isn't a "hormone". *sigh*

Perhaps ASP is a bigger actor in the cycle in and out of the adipocyte and insulin for the cycle within. The FA/trig cycle definitely includes release into the whole body, of which some portion is taken back up into the adipocytes, although more is cleared in the systemic tissues.

Man would I love to be a fly on the wall on a Taubes/Frayn conversation >8)

CarbSane said...

Sheesh ... my typos are bad today. That's new EDition!

Nigel Kinbrum said...

I was chuffed to see Jack Salway's name mentioned in Frayn's book. I have two of Salway's books. I recommend both of them although there is some overlap. Links to Amazon in How stuff works.

CarbSane said...

Chuffed? I suppose I could look that up in some "urban dictionary", but I'd rather make more work for you ;-)

Nigel Kinbrum said...

Oops! Chuffed (to bits) :-)

CarbSane said...

Thanks! Sounds like it would mean the opposite, kinda like miffed but that didn't make sense. :)

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