I have to admit, my eyes glaze over reading most of what Gary Taubes has to offer these days. His latest seemed so much more of the same old same old. Old paradigm, new paradigm ... research will never move forward until they embrace the new paradigm. Thousands of scientists can't be right when Gary Taubes knows they're wrong.
But Taubes tucked something new into his latest post that I missed on the first read:
In this paradigm, meals stimulate hormonal responses—insulin, in particular, either in the short term (glucose) or the long term (fructose)— and this in turn directly influences both the storage of fat and the oxidation of fatty acids elsewhere in the body.In recent lectures Gary has been turning his ire towards fructose/sugar as the ultimate cause of obesity. He has in the past tried to explain the Japanese away by claiming they eat very little sugar. I suppose compared to the SAD this is true, but they do eat sugar (and they don't eat brown rice either, but can't we cut Taubes some slack when he makes stuff up? Swallow one for the cause!) Myself and others have pointed out the problem with this and TWICHOO -- that being that fructose does not stimulate an insulin response. Therefore it does not fit into TWICHOO as stated in GCBC or WWGF . Is he about to change his tune a bit by introducing some long term influence of fructose on insulin behavior? His toothpick of a fork tine is bent so badly at this point he's gotta fashion something to do his cherry picking with. Only to do that, he'll have to do some more cherry picking.
TWICHOO sounded pretty darned strong in earlier lectures. Damn convincing were those many ways carbohydrates spike insulin leading to fat accumulation. Poor glycerol-3-phosphate! I feel bad for the molecule that showed such promise as a biochemical star. Only in recent lectures Gary's not rescinded any of the defunct sub-hypotheses formally, he's just left them out and hopes nobody will notice while he diverts attention trying to tear down a hypothesis that actually DOES explain the Pima! All in the interest of making WWGF readable, I suppose.
There is certainly evidence out there implicating large bolus fructose doses in the development of short term insulin resistance as measured by peripheral glucose disposal. Long term? Not so much. Meanwhile there's a lot of studies out there exonerating sugar as a seminal factor in the development of obesity. (Which should not be interpreted as any endorsement by yours truly of a high sugar diet). The livers of the LF (high sugar) fed rats in the CAF rat study don't look good for sugar. But speaking of that study, the relatively low carb high fat diet (45% lard) fared rather poorly. Stephan added some info in the comments about fat quality that might have impacted the results ... but then one must wonder if the fat quality in the CAF diet is equally altered by processing?
And here I was feeling a bit like Rush Limbaugh when Bill Clinton left office ... LOL (Not really, but I'm sure my detractors were wondering what I'd be blogging on when Taubes fell by the wayside. Seems we're not going to have to worry about that one for a while - grin!)