I'm hoping to get to my analysis/comments of the hyperinsulinemia paper in Cell , that's causing all the buzz on the internet lately, published up by tomorrow. Such posts require more attention to detail and seriousness than posts such as this one. But it's a nice little break from my real life grind at the moment to bring you a little commentary such as this post.
The LC position on insulin is getting to be downright ridiculous. But the title of the paper, "Hyperinsulinemia Drives Diet-Induced Obesity Independently of Brain Insulin Production" can be quickly read as "Insulin causes obesity", which led two LC docs to jump right in. First, Eades tweeted:
paul weston @paulhweston @DrEades " bless me, what do they teach them at these schools!" Digory Kirke
@KVoelks @DrEades have only read the lay interpretation you provided, but how the hell did that study make it into Cell Metabolism?
@bokkiedog @DrEades According to that article, dietary fat is the cause of excess endogenous insulin. Gosh.
@LaurentRA @DrEades but won't they (incorrectly) claim that high fat meals cause insulin spike as per the mouse study?
Michael Eades, M.D.
@DrEades @KVoelks I know. It beggars belief.
@aaronh @DrEades Did they report any new findings on the wetness of water?
@dean @DrEades @bryhams didn't they also break some story last year something about bears.. in the woods..
Mary Lewis @mem_lewis @DrEades @KVoelks high fat can mean and typically does with rodents fat+sugar. It didn't say 100% fat. I'm sure O6pufa and I bet sucrose.
Nice mockery there, eh? A followup tweet was not much better. But not to be one-upped, his cohort in metabolic crime, Diet Doctor Andreas Eenfeldt, took it a step further. In a post entitled "It's the Insulin, Stupid". Not only did he apparently not read the study, but he took the time to "doctor" the graphics from the paper! I mean really, how steeped in dogma do you have to be to stoop to this level?
Ummm ... OK ... I guess this means that Eenfeldt believes High Fat Diet = Bad Food ;-) Or rather that he doesn't respect the intelligence of his audience enough to present the original graphic that implicates a HFD for that study. (Not to mention respect for copyright and fair use laws where he has materially altered the content of a graphic without notice, and attributes it to Johnson by inference of linking to his study -- VERY bad form.) He writes:
The researchers, publishing the study in the high-impact journal Cell Metabolism, conclude that too much fat-storing insulin is a necessary cause of common diet-induced obesity (press release).
In humans the main cause of elevated insulin is eating too much junk carbohydrates.
BTW, I refer to people by first and/or last names when writing my blog. Some choose one or the other, I tend to mix and match. My choice should not be interpreted either way as inferring anything negative (some think last names can be disrespectful in a being-obnoxious way, while first names are often construed as disrespectful in a patronizing or demeaning way). But when interacting directly with someone on the internet, this isn't rocket science. You refer to someone by their first name or used/preferred pseudonym. Anything else is generally intentional and telling of the person doing so and their intent to demean, disrespect or something else. On Stephan's last post, Eenfeldt chimes in addressing him as "Guyenet".
Andreas Eenfeldt said...
Regarding your argument regarding the rare obese gentleman with normal insulin:Does finding a black swan suggest that all white swans are a myth?
Obviously there are many possible causes of obesity, not just one. But the most common by far seems to be hyperinsulinemia. And the large majority of obese people have abnormally high insulin, as you know.
I realize English is not his first language, but I believe Sweden follows similar salutatory norms. Even if not, this man has been around long enough to know better, so this was an affront, I believe deliberate, but perhaps subconscious. How fitting, then, that he discusses the color of swans, eh? I mean isn't Eades the one who goes on and on (and on and on) about Popper and his black swans? In this case the black swans are inconvenient to the shillerati, so now they should be ignored in favor of the white swans where they can hypocritically equate correlation with causation to advance their dogma.
If the simplistic hypothesis (not Johnson's, but the TWICHOOB's) is that high insulin causes fat accumulation and thus obesity, yes, black swans like the man pictured in Stephan's post are damning. As are LIRKO and the many cases where hyperinsulinemia peacefully coexists with the non-obese state. More on that hopefully tomorrow. Back to the real life stuff ...