Showing posts from November, 2018

The $12M NuSI/Ludwig Study: Part I: Critique of the Study Design

S UMMARY The results of the $12 Million Dollar NuSI-sponsored study, headed up by Dr. David S. Ludwig, are finally out.   Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: randomized trial While the good doctor is making the rounds touting them as evidence in support of the Carb-Insulin Hypothesis (TWICHOO in these parts), a review of the raw data made available to the public casts grave doubts on his victory lap.  This study built upon the "promising" results of the 2012 study:   Effects of Dietary Composition on Energy Expenditure During Weight-Loss Maintenance    This post focuses on comparisons of Study Design between these two studies, some improvements, and the ultimate failure that renders the primary outcome data suspect, if not outright useless.  (And I don't say that lightly!) Improvements: Study size Length of time on one test diet (20 weeks) vs. 4 weeks crossover on each diet w/o washout Protei

Why Aren't We Taking Anti-Obesity Drugs?

This post was prompted by the following article on Medscape Why Aren't We Prescribing Pills for Obesity? It is written by Caroline M. Apovian, MD  I'd encourage you to read this whole thing first, as I'm genuinely interested in that response. Additionally I'm curious as to whether or not your response changes after reading this blog post (or other sources I'm about to link to).

"Real Food Keto" Quips

Rather than formally reviewing Real Food Keto -- an abomination of a book written by Jimmy Moore and his "Nutritional Therapy Practitioner" wife Christine Moore -- I've decided to compile a collection of my tweets here in a blog post.  I'll sort from most recent, with the newest before the "page break" after each update.  Feel free to comment here, but I'm also embedding tweets if you wish to go respond on Twitter.   Some may include additional commentary, others just the tweet. Enjoy! This book is littered with nonsense about how low stomach acid causes everything from ass itching  to zygomycosis.   No doubt there will be more of these tweets coming! Fun #RealFoodKeto "facts" from @livinlowcarbman and his NTP wife. FACT: Lemon juice (mostly citric acid) gives it a pH ~2.  Add some to neutral water (pH 7), the lemon water will be less acidic (e.g. higher pH, closer to 7) but will not become alkaline (pH >7) #LCHF -raud pi