The Carb-Sane Asylum

BUMP - and due to time constraints but lots of comments already here, I've changed my mind on starting a Fat Summit thread and retitled this one.  I hope to put a "best of" video together in response to this tentatively titled The Fact Summit.  Thanks for all your participation! EDIT:  As of 2/16/16 we're at over 1200 comments (fun times!!) and for me, Disqus is slow to load in blogger.  To engage, you may wish to read/comment using this link   which goes directly to disqus. Lent begins on February 10th this year, so I have decided to engage in a 40 day fast beginning today, January 15th.   The fast officially ends on Valentine's Day at which point I will return to eating like 99% of humans on the planet. What will I be consuming during this fast?  Well I wouldn't want to kill my gut flora or get my electrolytes outta whack, so I have decided to include 1 cup (which might be two if my body tells me it needs it) of The Faker Foodie's organic, ...

Been reading a lot about leptin and leptin resistance lately and the recent theory that triglycerides cause leptin resistance.  Leptin is secreted by fat cells essentially in correlation to fat mass and it is supposed to tell us to stop eating when we have accumulated too much fat.  The leptin resistance theory of obesity is that our brains don't receive the leptin signal so we keep eating and get fatter. Triglycerides Induce Leptin Resistance at the Blood-Brain Barrier Abstract Obesity is associated with leptin resistance as evidenced by hyperleptinemia. Resistance arises from impaired leptin transport across the blood-brain barrier (BBB), defects in leptin receptor signaling, and blockades in downstream neuronal circuitries. The mediator of this resistance is unknown. Here, we show that milk, for which fats are 98% triglycerides, immediately inhibited leptin transport as assessed with in vivo, in vitro, and in situ models of the BBB. Fat-free milk and intralipid, a sourc...