Rapid Weight Loss Tanks Metabolism? The TBL Study
![Image](https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEikaL6d4mnnyvhTeCyYgq3znoYFRbytUiIWXDoBWLSIPxNKng76g8l0A5c7z2wKbRbAI6aQ8hLCqDsYw4wVjUrfTj7FUDOydvP-vXWwhER2j8r7MsACCaPO4uWrhL-C5e_2hEQ8nYkYdWk/s320/ScreenHunter_06+Apr.+30+07.27.gif)
Thanks to Yoni Freedhoff of Weighty Matters blog for providing me with the full text of this one. Check out his take on the results. Update 11/11/13: Full text now available free HERE . Context: An important goal during weight loss is to maximize fat loss while preserving metabolically active fat-free mass (FFM). Massive weight loss typically results in substantial loss of FFM potentially slowing metabolic rate. Objective: Our objective was to determine whether a weight loss program consisting of diet restriction and vigorous exercise helped to preserve FFM and maintain resting metabolic rate (RMR). Participants and Intervention: We measured body composition by dual-energy x-ray absorptiometry, RMR by indirect calorimetry, and total energy expenditure by doubly labeled water at baseline (n = 16), wk 6 (n = 11), and wk 30 (n = 16). Results: At baseline, participants were severely obese (×± sd; body mass index 49.4 ± 9.4 kg/m 2 ) with 49 ± 5% body fat. At wk 30,