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Sunday, September 19, 2010

Chylomicrons and HDL

Another one of those mostly bookmark posts with no commentary

Metabolic Fate of Chylomicron Phospholipids and Apoproteins in the Rat

The researchers injected radiolabeled chylomicrons into rats to determine the fate of the components.  The results:
Catabolism of chylomicrons is associated with a rapid transfer of phospholipid, apoA-I, and possibly apoA-IV into HDL. Chylomicron phospholipid appears to give rise to vesicles which are probably incorporated into preexisting HDL. Chylomicron surface components may be an important source of plasma HDL.


Ed Terry said...

Since rats have predominantly HDL as opposed to most people who have a higher LDL, how would this apply to people?

CarbSane said...

To be honest I'm not sure. Perhaps, however, this is why low fat diets tend to lower HDL and vice versa. Just putting it out there ...

Welcome to my blog Ed!

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