Twenty tips for interpreting scientific claims
It's not often I share journal articles without comment here anymore, but I just wanted to share this with my readers.
Twenty tips for interpreting scientific claims from Nature.
Twenty tips for interpreting scientific claims from Nature.
Comments
http://www.ncbi.nlm.nih.gov/pubmed/24176230
No control group. They simply measured changes from baseline after adopting a diet of "meat, poultry, seafood, eggs, cheese, oils, non-starchy vegetables, and small amounts of nuts, seeds, and berries."
Saturated fat, monounsaturated fat, protein and cholesterol intake increased. Carb, trans fat, fiber, energy intake and body weight decreased. Blood pressure dropped, forearm blood flow increased, FMD didn't change. Total cholesterol, high-density lipoprotein cholesterol (HDLC), LDL-C, or glucose did not significantly change over time. serum triglycerides were decreased by 36% at both 3 and 6 weeks. Both serum insulin and HOMA-IR decreased. No significant effect was determined for CRP, TNF-α, IL-6, IL-8, sVCAM-1, or MCP-1. However, both sESelectin and sICAM-1 decreased from baseline.
From what you write, it looks as though you were able to read the actual study. I'm wondering what the value of such a study is.
But it sure does look like someone spent money on producing this conclusion: some people who take statins did not die within six weeks of reducing carbohydrate intake.
Which is worth something, BTW. That's something you can take to the bank!
I think a 400+ cal/day deficit may be what they call a confounding variable here, and/or the increase in protein. Just sayin ;-)
I notice that the participants continued to take their regular dosage of medications for hypertension (9 participants), hypothyroidism (5 participants), and hyperglycemia (1 participant). They continued to take those medications without any changes during the study.
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